A customized blend to treat your
fine lines.

From wrinkles to breakouts - it’s time to get personal with your skin. Get dermatologist-selected ingredients in a treatment made for you.

  • Personalized plans
  • Powerhouse ingredients
  • Free 2-day shipping
  • Free, unlimited follow-ups
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Free, unlimited follow-ups

Whether you’re just starting your skincare routine, upgrading, or trying to find one that works—you’ll have questions. And that’s why we will be here every step of the way. You'll have unlimited free access to a healthcare professional with a proactive follow-up.

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How it works
  • Online visit You’ll start an online consultation by providing information about your general health and then you’ll tell the doctor or nurse practitioner all about your skin goals.
  • Personalization After your visit, if appropriate, a doctor or nurse practitioner will recommend a treatment option based on your priorities and skin type.
  • Ongoing care You’ll receive ongoing care and have free, unlimited follow-ups.

Skincare, simplified.

Now, there’s a smarter and simpler way to take care of your skin. If prescribed, your treatment will include a combination of dermatologist-selected ingredients that address fine lines and wrinkles, breakouts, dark spots, dullness, and skin texture. Your treatment might include the following powerhouse ingredients.

Tretinoin

Stimulates collagen production to give a more youthful appearance by treating age spots and reducing the appearance of fine lines.

Tretinoin should not be used by women who are pregnant, trying to get pregnant, or breastfeeding. Important Safety Information

Niacinamide

A member of the vitamin B family that improves the appearance of dark spots, red blotches, and skin yellowing.

Azelaic acid

Blocks redness and swelling by collecting unstable molecules that damage skin at the cellular level.

Azelaic acid can cause unwanted lightening of the skin if you have a darker complexion. Important Safety Information

Ceramides

Naturally found in the skin, ceramides support moisture retention in the skin’s outer layer.

Tranexamic acid

Topical tranexamic acid is widely used to help lighten dark spots.

Vitamin E acetate

An antioxidant that, when used topically, may help defend against signs of photoaging.

Magnesium ascorbyl phosphate (MAP)

Part of the vitamin C family, MAP can improve the appearance of dark spots.

Tranexamic acid

Topical tranexamic acid is widely used to help lighten dark spots.

A consultation, not another quiz.

When you finish answering general health questions—you’ll be connected with a U.S.-licensed doctor or nurse for a free consultation. And after your consultation—your doctor or nurse practitioner will recommend a personalized treatment plan.

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Frequently asked questions

Can I use prescription skin care products with my other skin care products?

The prescription skin care treatment recommended for you may be incorporated into your usual skin care regimen. If you are using other topical prescription medications, make sure to tell your doctor or nurse practitioner.

Dr. Mike Bohl, MD, MPH
Associate Director, Medical Content

Can I use prescription skincare products with my other skincare products?

Prescription skin care treatment recommendations are made with dermatologist selected ingredients. Examples include tretinoin, niacinamide, ceramides, vitamin E (acetate), azelaic acid, magnesium ascorbyl phosphate (MAP, a type of vitamin C), and tranexamic acid. There will not be any parabens, butylated hydroxyanisole (BHA), or formaldehyde in your prescription skin care.

Dr. Rachel Kwon
MD

When will I start to see improvement with my skin?

The timing of the effects of your treatment will be dependent on many factors, including your specific skin care goals (e.g. reducing the appearance of fine lines and wrinkles, helping prevent wrinkles, reducing redness, etc.), how severe your symptoms are, how well you tolerate the treatment, and others. It is also important to understand that for certain treatments, your skin may get worse before it gets better. Depending on the treatment you are prescribed, you will receive detailed information on what to expect.

Dr. Tzvi Doron
DO, Family Medicine

Simplify your skincare routine.

Why Rory for Skincare

Upgrading your skincare routine is possible with a customized night cream. Every bottle is custom-blended with thoughtfully chosen ingredients and delivered to your door.

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What our members are saying...

Rory's Nightly Defense has made a dramatic improvement in my skin. I've noticed a marked improvement in discoloration, my skin is very soft, my pores appear smaller, and my fine lines have been reduced.

Rory member Verified

I have been receiving compliments on how great my skin looks, there was a noticeable difference within a week of using the product. It has not been this clear or has looked this great in years. This is the longest I have gone without one breakout, too! I feel so much better and I have had a major confident boost.

Rory member Verified

Just this weekend (after roughly three weeks of using Nightly Defense) my friend commented on my skin's even complexion! I haven't had a breakout since using Nightly Defense either

Rory member Verified

I feel Nightly defense has definitely helped soothe my redness and acne scarring from past breakouts

Rory member Verified

Rory is the easiest and safest online prescription service I know of. The doctors and nurses are very helpful, and the shipping is fast and discrete.

Rory member Verified

I could not be any more pleased with the product or the company. The process of receiving the prescription was easy yet they put together the perfect regimen for me. I received the product within days and saw results within days after that. I can not say enough great things about the product or the company.

Rory member Verified

This product is more versatile than previous scripts I've gotten from my dermatologist. The other ingredients in the Nighty Defense allows me to use it almost year round whereas the other products were too harsh and I chose to only use in the winter.

Rory member Verified

LOVE the convenience. I recommend Rory to all my friends! It takes just five minutes for a personalized skincare cream AND it's just $75 for a three month supply... How can you beat that? The answer is you can't...

Rory member Verified

The above opinions were shared by members whose online visit and prescription medication were provided at no cost. Individual results with Nightly Defense may vary.
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Important Safety Information

Topical tretinoin

Read this information before you start taking tretinoin and each time you get a refill. There may be new information. This information does not take the place of talking with your doctor about your medical condition or treatment. If you have any questions about tretinoin, ask your doctor or pharmacist.

What is the most important information I should know about tretinoin?

Tretinoin is a topical medication that is used to treat (reduce the appearance of) fine lines and wrinkles on the face. It should not be used in pregnant or breastfeeding patients, or patients who are trying to get pregnant or are unsure whether they are pregnant. People using tretinoin should have an aggressive sun protection regimen including sunscreen (at least SPF 50), protective clothing, and sun avoidance whenever possible.

What is tretinoin?

Tretinoin is a topical medication that is used to treat (reduce the appearance of) fine lines and wrinkles on the face.

Who should not use tretinoin?

People who are pregnant or breastfeeding (including trying to get pregnant or are unsure whether they are pregnant) should not use tretinoin, as tretinoin has been associated with miscarriage and birth defects. Additionally, people with an allergy to tretinoin should not take tretinoin.

Before you take tretinoin, tell your healthcare provider if:
  • You are pregnant or breastfeeding
  • You have eczema
  • You are sensitive to sunlight or easily sunburned
  • You have any of the following conditions that may increase sensitivity to sunlight:
  • Lupus (e.g. systemic lupus erythematosus, cutaneous lupus erythematosus)
  • Albinism
  • Porphyria
  • You take medication that increases sensitivity to sunlight, including but not limited to:
  • Tetracyclines (e.g. doxycycline, tetracycline, minocycline)
  • Sulfonylureas (e.g. acetohexamide, chlorpropamide, glimepiride, glipizide, glyburide)
  • Thiazide diuretics (e.g. hydrochlorothiazide/HCTZ or any drug containing HCTZ, chlorthalidone, bendroflumethiazide, methyclothiazide, metolazone), phenothiazines (chlorpromazine, promethazine, perphenazine, thiethylperazine, thioridazine)
  • Fluoroquinolones (e.g. ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin)
  • (Moderate) Benzoyl peroxide can potentiate skin irritation caused by topical tretinoin. Avoid using in the same areas as topical tretinoin.
  • (Moderate) Salicylic acid: dry skin and mucus membranes are common side effects of retinoid therapy. Using retinoids concurrently with topical drying agents like salicylic acid can increase the drying effects of retinoids.
  • (Moderate) St. John's Wort (hypericum perforatum): there is a theoretical risk of additive photosensitizing effects from concurrently using St. John's wort with other photosensitizing drugs like retinoids.
  • You are receiving photodynamic therapy with photosensitizing agents including but not limited to porfimer, aminolevulinic acid, verteporfin, methoxsalen.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use tretinoin?

Use tretinoin exactly as your doctor tells you.

Use the formula at nighttime, before bed (UV light in sun degrades tretinoin). Wash your face using a gentle cleanser and pat dry. Let the skin dry completely before applying the cream. Apply a thin layer to the affected areas. Avoid direct contact with your eyes and eyelids (under the eyes is ok). Wash your hands after applying.

Repeat 2–3 times a week as tolerated to begin with, then gradually increase to nightly use, or as directed by your doctor.

Avoid exposure to the eyes, including eyelids, mouth, angles of the nose, and mucous membranes. If contact with the eyes occurs, rinse thoroughly with large amounts of water.

Apply only to affected areas (exposure to unaffected skin may cause irritation).

What are the possible side effects of tretinoin?

People who use tretinoin may experience a number of side effects, including itching, burning, redness, and peeling, sometimes referred to as “retinoid reaction.”

Tretinoin is known to cause miscarriage and birth defects and should never be used in people who are pregnant, breastfeeding, or trying to get pregnant.

Tretinoin also makes the skin more sensitive to light, so daily sunscreen in tretinoin users is a must.

Less common side effects include:

  • Erythema nodosum (severe skin inflammation)
  • Edema (swelling)
  • Rash
  • Skin hyperpigmentation (dark spots)
  • Skin hypopigmentation (light spots)
General information about tretinoin

Medicines are sometimes prescribed for purposes that are not in the patient leaflet. Do not use tretinoin for a condition for which it was not prescribed. Do not give tretinoin to other people, even if they have the same symptoms you have. It could harm them.

This page summarizes the most important information about tretinoin. If you would like more information about tretinoin talk with your doctor. You can ask your doctor or pharmacist for information about tretinoin that is written for health professionals.

Important Safety Information

Topical azelaic acid

Read this information before you start taking azelaic acid and each time you get a refill. There may be new information. This information does not take the place of talking with your doctor about your medical condition or treatment. If you have any questions about azelaic acid, ask your doctor or pharmacist.

What is the most important information I should know about azelaic acid?

Azelaic acid is a topical medication that is used to treat redness and acne on the face. It should be used with caution in people with darker complexions, as it is not well studied in those populations and may cause hypopigmentation (skin lightening).

What is azelaic acid?

Azelaic acid is a topical medication that is used to treat redness and acne on the face.

Who should not use azelaic acid?

Azelaic acid should not be used in people who have had a previous allergic reaction to azelaic acid.

Before you take azelaic acid, tell your healthcare provider if:
  • You are pregnant or breastfeeding
  • You have asthma or have ever had asthma

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use azelaic acid?

Wash face and pat dry. Apply a thin layer of cream to affected areas on your face and massage gently into the skin. Wash hands after applying. Do not cover the area after applying. Repeat nightly before bedtime.

If you have a cold sore (oral herpes), avoid applying the cream to the area of the cold sore. Exacerbations of cold sores have been reported.

Avoid contact with the mouth, eyes, and other mucous membranes. If exposure to the eye occurs, wash with large amounts of water and contact your doctor or nurse practitioner if irritation persists.

What are the possible side effects of azelaic acid?

Azelaic acid can cause itchy dry skin or skin irritation.

Worsening or deterioration of asthma has been reported in patients treated with azelaic acid. If you have asthma and experience any signs of an asthma attack (i.e., shortness of breath, wheezing), tell your doctor or nurse practitioner.

Less common side effects include:

  • Angioedema (allergic reaction involving severe swelling)
  • Erythema (redness)
  • Edema (swelling)
  • Contact dermatitis
  • Wheezing
  • Dyspnea (shortness of breath)
  • Ocular inflammation
  • Paresthesias (abnormal sensation)
  • Rash
  • Skin hypopigmentation
  • Hypertrichosis (increased hair growth)
  • Urticaria (hives)
General information about azelaic acid

Medicines are sometimes prescribed for purposes that are not in the patient leaflet. Do not use for a condition for which it was not prescribed. Do not give azelaic acid to other people, even if they have the same symptoms you have. It could harm them.

This page summarizes the most important information about azelaic acid. If you would like more information about azelaic acid talk with your doctor. You can ask your doctor or pharmacist for information about azelaic acid that is written for health professionals.